The relevance of this study is associated with the acute shortage of organs for transplantation, which is a widespread issue in healthcare systems worldwide.The purpose of the study is to identify potential grip ways to increase the number of individuals providing posthumous consent for donation and, consequently, the availability of donor material
The inflammatory response in the injured spinal cord, an immune privileged site, has been mainly Mists associated with the poor prognosis.However, recent data demonstrated that, in fact, some leukocytes, namely monocytes, are pivotal for repair due to their alternative anti-inflammatory phenotype.Given the pro-inflammatory milieu within the traumat
Apert syndrome is a rare genetic disorder, characterized by premature fusion of skull sutures, mid-face hypoplasia and syndactyly of the hands and feet.It is inherited as autosomal dominant or sporadic and is associated with increased paternal age.It arises from mutations in the fibroblast growth factor receptor Hand Pulse Sensor Wire 2 gene on chr
The combination of folinic acid, 5-fluorouracil, oxaliplatin and/or irinotecan (FOLFOXIRI) is the standard of care for metastatic colorectal cancer (CRC).This strategy inhibits tumor growth but provokes drug resistance and serious side effects.We aimed to improve FOLFOXIRI by optimization of the dosing and the sequence of drug administration.We emp